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Uses

Tadalafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED).

Precautions

Do not use if you have had an allergic reaction to sildenafil or any of the ingredients in the product. Do not use if you have an allergy to any medicines or other substances. Do not use if you have ever had an allergic reaction to sildenafil ( others ) in the past. Do not use if you have ever had an erection that lasted more than 4 hours ( lasts more than 4 hours (3 hours (1 hour (1 hour (1 hour (1 hour (1 hour (1 hour)). This medicine is only available with a prescription). It is not a substitute for medical advice. You may ask doctor or pharmacist again if you need further testing or treatment. Do not use if you have or have had any of the serious side effects that can happen in rare.

Do not use if you are taking a medicine called nitrates (commonly known as "poppers").

Warnings

If you are 65 years of age or older: If your erection lasts more than 4 hours (3 hours (1 hour (1 hour). If this occurs before or after taking sildenafil, do not take it. Do not take sildenafil if the erection lasts longer than 4 hours (3 hours). Do not take sildenafil if you are taking nitrates (commonly known as "poppers") in any form (including, but not limited to, tablet, capsule, patch, spray, injection, or by injection).

If you have ever had an allergic reaction to sildenafil ( others) or any of the ingredients in the product. Do not use if you have an erection that lasted more than 4 hours (3 hours (1 hour). This may happen, but it is not required to have an erection.

If you are taking medicines called alpha-blockers to treat high blood pressure, or you have used certain medical treatments before. Alpha-blockers may cause dizziness or drowsiness. Do not use sildenafil if you are dizzy or drowsy. Do not use if you are using or have used other treatments for ED in the past 4 to 6 hours (even if your erection has not yet developed). Do not use if you have any of the serious side effects that can happen while taking this medicine. If you have any of the serious side effects that can happen while taking this medicine. These include: fast/palpitations heartbeat muscle weakness or paralysis. If you experience any of the symptoms of an allergic reaction, stop taking the medicine and contact your doctor immediately. If you have recently had heart surgery, you may be taking other medicines called alpha-blockers to treat high blood pressure.

Possible Side Effects

These effects are rare and may happen, but they are possible and should be discussed with your doctor. If you do not have an erection, or if it lasts longer than 4 hours (3 hours). If this happens, stop taking the medicine and seek a doctor's advice. This medicine may cause other side effects, including: loss of appetite, nausea/vomiting, loss of the ability to get or keep an erection. These side effects may not be serious enough to require immediate medical attention and may improve with time. If you experience any of the serious side effects that may happen while taking this medicine, you may require immediate medical attention and contact your doctor.

Do not use if you are 65 years of age or older: If your erection lasts more than 4 hours (3 hours). Do not take sildenafil if you have any of the serious side effects that can happen while taking this medicine.

Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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Sildenafil citrate, commonly known by the brand name, is a prescription-only medication used to treat erectile dysfunction (ED) in adult men. It is also used to treat pulmonary arterial hypertension (PAH) in adults by increasing blood flow to the lungs. The safety and effectiveness of sildenafil in treating ED has not been studied against other ED medications like tadalafil or vardenafil.

Sildenafil is available by prescription only. Not approved by the MHRA or the FDA.

Sildenafil, the brand name for Viagra, NHSolanst and many other pharmaceutical manufacturers produce and health brands enter drug markets for prescription-only medicines.

The Science Behind the Potency of Sildenafil Citrate

Sildenafil Citrate is a PDE-5 inhibitor that enhances blood flow to the genital area, while simultaneously inhibiting PDE5 enzymes, which promote the production of nitric oxide and increase the production of prostaglandins, which are responsible for relaxing the muscles of the penis and improving blood flow to the cavernous bodies, among other functions. This study was conducted to understand the mechanisms that underlie the mechanism of action of sildenafil citrate, as well as the potential benefits of this drug for improving erectile function. The study was conducted in accordance with the principles of the Declaration of Helsinki and its later amendments. The study protocol was approved by the Ethics Committee of the National Center for Drug Evaluation and Research (NCEIR). All patients provided written informed consent.

A randomized, double-blind, placebo-controlled study was performed in 80 male patients, between 18 and 40 years of age, with no history of erectile dysfunction or other causes. The study was conducted in the male department of the National Institute for Health and Care Research (NIHR) and included the following groups: (1) Patients with erectile dysfunction, (2) Patients who were taking oral sildenafil, and (3) Patients who were not. The patients had no history of cardiovascular disease, kidney disease, blood pressure or diabetes. The patients were given sildenafil citrate 20 mg orally, with or without food, with or without alpha-blockers, or with other medications for erectile dysfunction.

Sildenafil citrate has been shown to have a greater positive effect on penile erection than other agents in the studies. The sildenafil citrate-treated group showed greater improvement in erectile function (EDI and EDRI) as compared with the placebo group. However, no difference was observed in the number of premature ejaculation (PE) episodes among the groups. The results indicate that sildenafil citrate improves blood flow to the penile tissue, while the other agents do not, and may result in reduced performance of erections. This study showed that the effects of sildenafil citrate could be further improved by adding alpha-blockers to the treatment.

Sildenafil citrate has been shown to be effective in treating erectile dysfunction in adult males. Sildenafil citrate is a PDE-5 inhibitor that has been shown to be more effective than alpha-blockers, and thus, has been shown to be more effective than a PDE-5 inhibitor in treating the symptoms of erectile dysfunction.

The Effect of Sildenafil Citrate on the Blood Flow to the Penile Tissue

Sildenafil citrate, with the aim to increase blood flow to the penile tissues, has been shown to have a positive effect on penile erection. The results of the study indicated that the effects of sildenafil citrate were more significant in the group that received alpha-blockers and in the group that received sildenafil citrate.

The mechanism of action of sildenafil citrate is similar to that of alpha-blockers. Alpha-blockers decrease the production of prostaglandins, which are important for regulating the body's natural response to stress and for promoting the growth of the prostate gland. These effects on the prostaglandins are thought to occur because sildenafil citrate relaxes the muscles of the penis, and the relaxation of the penile tissue leads to an increase in blood flow to the penile tissues.

The most common side effects of sildenafil citrate are: headache, flushing, nasal congestion, dizziness, and stomach upset. The effect of sildenafil citrate on erectile function is not known.

Sildenafil citrate blocks the effects of alpha-blockers, which are produced by the prostate gland, thus reducing the production of prostaglandins. In addition, sildenafil citrate blocks PDE-5 enzymes, which are responsible for producing prostaglandins, and thus, the reduction in blood flow to the penile tissues is a side effect of sildenafil citrate.

Uses of Sildenafil

Sildenafil is used to treat pulmonary arterial hypertension and to improve penile functions.

Therapeutic Category

Sildenafil: Phosphodiesterase type 5 (PDE 5) inhibitors

How Sildenafil works

Sildenafil works by blocking the effects of certain enzymes (PDE5) within the body which limits blood flow to the lungs and penis. As a result, it causes widening of blood vessels (arteries) supplying these organs, increases blood flow and oxygen supply and improves their functions.

Common side effects of Sildenafil

  • headache
  • flushing
  • indigestion, diarrhoea
  • pain in the arms or legs
  • vision problems
  • flu-like symptoms, inflammation of the sinuses, fluid retention
  • difficulty in sleeping, anxiety, shaking
  • sensation of pins and needles
  • vertigo (spinning sensation)
  • nosebleed, runny nose, cough, stuffy nose
  • nausea, vomiting, stomach inflammation, heartburn, piles, abdominal distension, dry mouth, diarrhea
  • hair loss
  • skin redness, night sweats
  • muscle pain, back pain
  • increased erections

When to consult your doctor

Consult your doctor if you experience:

  • prolonged or painful erection (priapism)
  • sudden decline or loss of vision
  • fits or seizures
  • pneumonia, abnormal heartbeat, chest pain, fainting
  • infections (viral infection of the gut, urinary tract infections and tooth cavities)
  • fits, hearing impairment inflammation of digestive tract

Health Tips for Sildenafil

  • Sildenafil is not suitable for use in women
  • Sildenafil is generally more effective when taken on an empty stomach
  • Avoid consumption of alcohol or grapefruit juice while taking Sildenafil as it may increase its side effects
  • Avoid using recreational drugs (like amyl nitrate, etc.) while taking sildenafil as it may cause a dangerous drop in blood pressure
  • Sildenafil should not be taken more than once in a 24-hour period
  • Before taking Sildenafil, inform your doctor if you have any liver, kidney, or heart problems
At Brush and Ocular Health we do not provide a consultation. We (the Patient and General the provider) will make sure that the Patient and General is accurate when it comes to when and how often we receive your medication. If you want to learn more about, please see our:. For more information, see the 'Disclaimer' tab in our @.)

How to take Sildenafil

Take this medication by mouth (acerbates timing) for the stipulated duration as advised by your doctor. Your dose will be cyclically and conventionally taperred based on your overall condition and how well you tolerate it. For optimal results, it is recommended to take this medication at the same time every day as directed. For the best results, regularly regularise your medication schedule. Avoid taking more than this in a 24-hour period. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, you should wait at least 10 minutes before taking the next dose.

Sildenafil (generic Equiallergy Relief tablets)

A combination of 50mg tablet and 100mg tablet every 4 hours (occurs 4 times a day as well as by medical route).

Tri- and combination sildenafil tablets contain 50mg tablet and 100mg tablet every 4 hours (occurs 4 times a day).

Sildenafil is indicated in children aged <18 years.

Use non-pharmacological means of treating patients with Equiallergy Relief tablets to ensure you are getting the maximum benefit from this medication.